$ 767.57
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Human Fibronectin (HFN) is a widely distributed glycoprotein that is used as a substrate to promote attachment of cells through its central-binding domain RGD sequence. HFN is a product of most mesenchymal and epithelial cells and is present in both the ECM and plasma. The principal function of HFN appears to be in cellular migration during wound healing and development, regulation of cell growth and differentiation, and haemostasis/thrombosis.Applications include:Promotion of cell attachment and spreadingRapid expansion of cell populationsSerum-free or reduced-serum cultureCell adhesion assaysStudies of effects of HFN on cell behaviorImproving survival of primary cells in cultureSource: Human plasmaNOTE: Source material tested for hepatitis B antigen and HIV-1 antibodyQuality ControlTested for ability to promote attachment and spreading of BHK-21 hamster kidney cellsTested and found negative for bacteria and fungiFibronectin purity >90% by SDS-PAGEStorage: 2°C to 8°C. Do not freeze.