Antibiotic-Antimycotic (100X), Solution contains penicillin, streptomycin, and Amphotericin B to prevent cell culture contamination, Case of 20

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Gibco™ Antibiotic-Antimycotic is used to prevent bacterial and fungal contaminationSolution contains 10,000 units/mL of penicillin, 10,000 µg/mL of streptomycin, and 25 µg/mL of Gibco Amphotericin BThe antibiotics penicillin and streptomycin prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteriaAmphotericin B prevents fungal contamination of cell cultures due to its inhibition of multi-cellular fungus and yeastPenicillin was originally purified from the fungus Penicillium and acts by interfering directly with the turnover of the bacteria cell wall and indirectly by triggering the release of enzymes that further alter the cell wallStreptomycin was originally purified from Streptomyces griseus and acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteriaStore at -5°C to -20°C