(ASN670,STA671,VAL672)-AMYLOID ,Each

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(ASN670, STA671, VAL672)-AMYLOID B/A4, 1mg. Amyloid precursor protein (APP) ▓_x0003_-secretase from human brain cleaves full-length APP at the amino terminus of the amyloid ▓_x0003_-protein (A▓_x0003_) sequence, thus leading to the generation and extracellular release of ▓_x0003_-cleaved soluble APP and a corresponding cell-associated carboxy-terminal fragment. The subsequent cleavage of the C-terminal fragment by │_x0003_-secretase(s) leads to the formation of A▓_x0003_. This new peptide represents a potent substrate analog inhibitor of APP ▓_x0003_-secretase with IC50 = 30 nM. CAS: 350228-37-4 C73H118N16O27 FW: 1651.83. Synonym: (Asn670,Sta671,Val672)-APP770 (662-675)