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Reacts with the heavily glycosylated 110kDa lysosomal-associated membrane protein, LAMP-1. LAMP-1 is a widely expressed intracellular antigen. It is also expressed on the surface of activated platelets, PHA-activated lymphocytes and some tumor cell lines, including U937 and KG1a. LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion. LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines, and are able to display sialyl Le[x] termini. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.Host Species: MouseClone: H4A3Isotype: IgG1 κSpecies Reactivity: HumanIntracellular Staining
