CD20 Mouse anti-Human, BB515, Clone: 2H7, BD, Mouse Monoclonal Antibody, Each

Details

The 2H7 monoclonal antibody specifically binds to CD20 that is encoded by the MS4A1 (Membrane-spanning 4-domains, subfamily A, member 1) gene. CD20 is a 33-37 kDa unglycosylated four-transmembrane phosphoprotein. CD20 is expressed on pre-B-cells, resting and activated B cells and follicular dendritic cells but not on plasma cells. Low level CD20 expression is observed on a small subset of normal circulating T lymphocytes. The CD20 molecule is involved in the regulation of B-cell activation.