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CD34 (Anti–HPCA-1), clone My10, is derived from the hybridization of mouse Sp2/0-Ag14 cells with spleen cells of BALB/c mice immunized with the human cell line KG-1a. The CD34 antigen is a single-chain transmembrane glycoprotein, Mr 105 to 120 kilodaltons (kd). The antigen is associated with human hematopoietic progenitor cells and is a differentiation stage–specific leucocyte antigen. Clone My10 and clone 8G12 recognize two distinct CD34 epitopes; at least three epitopes have been identified.The CD34 antigen is a single-chain transmembrane glycoprotein, Mr 105 to 120 kilodaltons (kd). The antigen is associated with human hematopoietic progenitor cells and is a differentiation stage–specific leucocyte antigen. Clone My10 and clone 8G12 recognize two distinct CD34 epitopes; at least three epitopes have been identified.
