CD49a Hamster anti-Rat/Mouse, PerCP-Cy5.5, Clone: Ha31/8, BD, Hamster Monoclonal Antibody, Each

Details

The Ha31/8 monoclonal antibody specifically binds to the 180-kDa integrin α 1 chain (CD49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin β 1 subunit (CD29) to form the α 1β 1 (complex known as VLA-1). VLA-1 has been reported to be expressed on activated T cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The Ha31/8 monoclonal antibody is specific for both rat and mouse CD49a. It has been reported that Ha31/8 antibody can block VLA-1-mediated binding of rat cells to collagen.