CD49e Rat anti-Mouse, NA/LE, Unlabeled, Clone: 5H10-27, BD, Rat Monoclonal Antibody, Each

Details

The 5H10-27 (MFR5) antibody reacts with the α; 5 chain of the integrin α;5 β; 1 fibronectin receptor (CD49e/CD29, VLA-5) on thymocytes, activated T lymphocytes, mast cells, and a variety of mouse cell lines, but not splenocytes. Soluble 5H10-27 (MFR5) antibody has been reported to inhibit VLA-5–mediated functions in vitro. In addition, immobilized mAb 5H10-27 (MFR5) has been demonstrated to costimulate the proliferative response of CD8 T cells to plate-bound anti-CD3e antibody.