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Specifications MDL Number: MFCD00130890Purity: >=95% based on Mol. Wt. 12,327 basisStorage: -20CApplication: Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.Biochem Physiol Actions: The ready interconversion of cytochrome c between ferrous and ferric states makes it an efficient biological electron carrier. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal link in the respiratory chain, it forms the essential electron-bridge between the respirable substrates and oxygen.Quality Level: PREMIUMAssay: ≥95% based on Mol. Wt. 12,327 basisMol. Wt.: mol wt 12327 DaStorage Temp.: −20°CGene Information: cow ... CYC1(512500)
