Calbiochem α-Amyloid Precursor Protein Modulator, A cell-permeable benzolactam derived PKC activator (K, Each

Details

A cell-permeable benzolactam derived PKC activator (Ki = 11.9nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100nM in human fibroblast AG06848. Displays a marked loss of tumor promoting activity.