GATA3 Mouse, Alexa Fluor 647, Clone: L50-823, BD, Mouse Monoclonal Antibody, Each

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GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This ∼50-kDa nuclear protein regulates the development and subsequent maintenance of multiple tissues. GATA3 is involved in the development of T lymphocytes (regulates T cell receptor subunit gene expression) and the differentiation of mature T cells to become Th2 cells. The expressed levels of normal or mutant GATA3 are also associated with the behaviors of various cancer cells including estrogen receptor-positive breast carcinoma cells.