(GLY21)-ABETA-PROTEIN (1-40) ,Each

Details

(GLY21)-AMYLOID B-PROTEIN (1-40)^ 0.5mg Contrary to ▓_x0003_-amyloid peptides mutated at position 22 (Dutch, Italian, Arctic mutants) the Flemish mutation (A21G ) shows a decreased tendency to aggregate and a reduced neurotoxicity. In the studies of Betts and Tsubuki, A21G was degraded significantly more slowly by neprilysin than the wild-type A▓_x0003_ 1-40 and the E22 mutants. The relative resistance to proteolytic degradation may account for the pathogenicity of the A▓_x0003_ mutant. CAS: 154362-03-5 C193H293N53O58S FW: 4315.84 . Synonym: Amyloid b-Protein (1-40) Flemish Mutation, Amyloid b-Protein (1-40) A21G