HLA-ABC Mouse anti-Human, Brilliant Violet 711, Clone: G46-2.6, BD, Mouse Monoclonal Antibody, Each

Details

The G46-2.6 monoclonal antibody specifically binds to a monomorphic epitope on the alpha chain of major histocompatibility (MHC) HLA Class I antigens. Class I MHC antigens are widely distributed on human nucleated cells. The antibody was conjugated to BD Horizon BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 711-nm. BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors. However, the spillover can be corrected through compensation as with any other dye combination.