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(MET186)-MELANOCYTE PROTEIN PMEL17 ^ 1mg This modified sequence of the gp100 epitope gp(209-217) (H-4106), in which a methionine replaced the natural threonine at position 2, bound to the HLA-A2 molecule with greater affinity than the unmodified peptide and was shown to have an increased ability to generate melanoma-reactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. This synthetic peptide hold promise for the development of novel cancer immunotherapies. CAS: 181477-43-0 C47H74N10O14S FW: 1035.23 . Synonym: (Met186)-Melanocyte Lineage-Specific Antigen GP100 (185-193) (human, bovine, mouse), (Met186)-Melanoma-Associated ME20 Antigen (185-193) (human, bovine, mouse), (Met186)-ME20M/ME20S (185-193) (human, bovine, mouse), (Met186)-ME20-M/ME20-S (185-193) (human, bovine, mouse), (Met186)-95 kDa Melanocyte-Specific Secreted Glycoprotein (185-193) (human, bovine, mouse), Disomotide
