MPEP hydrochloride, Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors, Each
$ 418.76
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Details
MPEP hydrochloride is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.
Additional Information
SKU | 10176342 |
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UOM | Each |
UNSPSC | 41116105 |
Manufacturer Part Number | 1212/10 |