MSTFA and MSTFA 1% TMCS Silylation Reagent, Each

Details

Use Thermo Scientific™ MSTFA and MSTFA 1% TMCS Silylation Reagent for GC analyses of early eluting compounds that would otherwise be obscured in the chromatogram. MSTFA, the most volatile TMS-amide available, and its byproduct N-methyltrifluoroacetamide typically elute with the solvent front, allowing TMS derivatives of small molecules to be analyzed. Addition of Thermo Scientific™ TMCS aids derivatization of amides, secondary amines, and hindered hydroxyls not derivatized by MSTFA alone.Trimethylsilyl donor strength comparable to BSA and BSTFAReacts to replace labile hydrogens on a wide range of polar compounds with a Si(CH3)3 groupUsed to prepare volatile and thermally stable derivatives for GC and MSVolatile byproduct, N-methyltrifluoroacetamide, has an even lower retention time than MSTFAOften TMS derivatives of small molecules can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent frontAddition of Thermo Scientfic TMCS aids derivatization of amides, secondary amines and hindered hydroxyls not derivatized by MSTFA alone