Rab11 Mouse, Unlabeled, Clone: 47, BD, Mouse Monoclonal Antibody, Each

Details

The Rab proteins are small GTP-binding molecules that are localized to specific intracellular vesicles and organelles. It has been proposed that Rab proteins cycle between GTP- and GDP-bound forms and that this is related to their function as regulators of vesicular traffic. The Rab11 gene encodes a 24 kDa protein of 214 amino acids that has been detected in liver, brain, testis, spleen, and heart. Rab11 protein was isolated from the golgi-microsomal fraction of rat liver and has been detected in the Trans-golgi Network, secretory vesicles, and the pericentriolar recycling endosomes. The distribution of Rab11 indicates that this small protein is involved in regulating traffic at the Golgi complex.