Pinometostat (Epz5676) 10mg 1380288-87-8, Each

Details:

EPZ-5676 is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferaseDOT1L with Ki of 80 pM, demonstrating > 37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.