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Specifications Synonyms: (2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrochloride hydrateCAS Number: 100938-10-1Formula: C21H38N4O8 · HCl · xH2OFormula Weight: 511.01 (anhydrous basis)Linear Formula: C21H38N4O8 · HCl · xH2OMDL No.: MFCD00150636Purity: >=97% (HPLC)Storage: -20CBeilstein Registry Number: 8888370UNSPSC Code: 12352202General description: Chemical structure: peptideBiochem/physiol Actions: It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.Biochem/physiol Actions: It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.RIDADR: NONH for all modes of transportWGK Germany: 3
