HER-3/c-erbB-3 Ab-2 Mouse Monoclonal Antibody, HER-3/c-erbB-3 Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results, Each

Details

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents. Host Species: MouseClone: 2F12Isotype: IgG2a/κSpecies Reactivity: Human, Cow, Rat and Mouse. Others not tested.Epitope: aa 1295-1323Immunogen: Recombinant rat HER-3/c-erbB-3 oncoproteinMolecular Weight: 185kDaPositive Control: T47D cellsCellular Localization: Cytoplasmic and membrane Recommended for:Western BlottingImmunoprecipitation (Native and denatured) Note:USA: RUO; Int'l: RUO