AZD 3988, Potent and selective DGAT-1 inhibitor, Each
$ 3,949.57
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Details
AZD 3988 is a potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable.
Additional Information
| SKU | 10260318 |
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| UOM | Each |
| UNSPSC | 41116105 |
| Manufacturer Part Number | 4837/50 |
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