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IWP 12, Potent PORCN inhibitor; active in vivo, Each

1,915.28

Details

IWP 12 is a potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC50 = 15 nM). Inhibits Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. Blocks zebrafish tailfin regeneration in vivo.

Additional Information

SKU 10269417
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5279/50