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SIS3, Selective Smad3 inhibitor; inhibits TGF-βR1 signaling, Each

3,039.32

Details

SIS3 is a selective Smad3 inhibitor; attenuates TGF-β1-dependent Smad3 phosphorylation and DNA binding. Has no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. Inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Also inhibits TGF-β2-induced endothelial cell differentiation in iPSCs.

Additional Information

SKU 10264406
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5291/50