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Specifications Synonym: 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Irgasan, TriclosanCAS Number: 3380-34-5Empirical Formula (Hill Notation): C12H7Cl3O2Molecular Weight: 289.54Beilstein Registry Number: 2057142EC Number: 222-182-2MDL Number: MFCD00800992Analysis Note These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.Application A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products.Biochem/physiol Actions Irgasan is a broad spectrum antimicrobial agent. It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.General 'Certified Fluka® pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.Other Notes This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).Legal Information FLUKA is a registered trademark of FLUKA GmbHGrade: certified reference materialPharmacopeia Traceability: traceable to USP 1682206
